The Institute for Infection and Immunity is populated by investigators with expertise in the areas of:

  • Host-pathogen interactions
  • Immunology and host defense
  • Vaccine development
  • Outcome studies in clinical infectious diseases
  • Clinical studies in patients with HIV/AIDS

This translational research ranges from laboratory based and preclinical investigation to phase IV clinical trials. Specific areas of research include:

  • Pathogenesis of infections due to
    • Candida
    • Aspergillus
    • Mucorales
    • Staphylococcus aureus
    • Streptococcus
  • Corneal wound healing
  • Antimicrobial peptides
  • Host microbiome
  • Host cell invasion
  • Therapeutic antibodies
  • Vaccines against fungi and bacteria
  • Membrane protein-lipid interactions
  • Antiretroviral therapy
  • Urinary tract infections
  • Skin and soft tissue infections

Members of this group have developed the first fungal vaccine to succeed in a clinical trial. This vaccine is also in phase II testing for prevention of Staphylococcus aureus colonization and skin and soft tissue infection in military recruits.

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Infection and Immunity
Infection and Immunity
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Infection and Immunity
Infection and Immunity
Infection and Immunity
Infection and Immunity
Infection and Immunity
Infection and Immunity