Sheng-Xing Ma, MD, PhD
Professor in Residence of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA
Biochemistry and physiology of nitric oxide
Research DescriptionDr. Ma's research focuses on the biochemistry and physiology of nitric oxide and related biomolecules. He studies the biocapture of signal transduction cascades over skin acupuncture points/meridians as a translational research tool to assess diseases (obesity, hypertension, diabetes, and congestive heart failure) and to elucidate effects and mechanisms of mind-body practices. Additionally, he is interested in the neural control of sympathetic/cardiovascular functions and mechanisms of acupuncture via nitric oxide related signaling systems in the dorsal column pathway. His research projects encompass a broad spectrum of multidisciplinary techniques ranging from physiology/pharmacology, biochemistry, molecular biology, and histochemistry to integrative research in both animal models and human studies.
- MD, 1976, Sun Yat-Sen University of Medical Sciences, Guangzhou, China
- MS, 1982, China Academy of Chinese Medical Sciences, Beijing, China
- PhD, 1991, University of Iowa, College of Medicine, Iowa City, IA
Recent and/or Significant Publications
- Ji B, Hu J, Ma S. Effects of electroacupuncture Zusanli (ST36) on food intake and expression of POMC and TRPV1 through afferents-medulla pathway in obese prone rats. Peptides. 2012 Oct 29. pii: S0196-9781(12)00440-8. doi: 10.1016/j.peptides.2012.10.009.
- Ma SX, Li XY, Smith BT, Jou NT. Changes in nitric oxide, cGMP, and nitrotyrosine concentrations over skin along the meridians in obese subjects. >Obesity (Silver Spring). 2011 Aug;19(8):1560-7. Epub 2010 Dec 9.
- Hu J, Choo HJ, Ma SX. Infrared heat treatment reduces food intake and modifies expressions of TRPV3-POMC in the dorsal medulla of obesity prone rats. Int J Hyperthermia. 2011;27(7):708-16. Epub 2011 Oct 3