Pathophysiology and therapy of cerebral cavernous malformation syndrome
Research DescriptionThe Stockton Lab's research focuses on vascular diseases, and identifying disrupted endothelial signaling from gene mutations producing vascular malformations, such as Cerebral Cavernous Malformations, and Hereditary Hemorrhagic Telangiectasia. Her current work is in identifying novel endothelial signaling using in vitro biochemistry and cell biology, mouse disease models, and analysis of resected human lesions.
- BSc, California State University Bakersfield
- PhD, University of Massachusetts Amherst, Amherst, MA
Recent and/or Significant Publications
- Plummer ST, Wang Q, Bohn PW, Stockton R, Schwartz MA. Electrochemically Derived Gradients of the Extracellular Matrix Protein Fibronectin on Gold. Langmuir, 2003 19(18), 7528-7536.
- Green JA, Stockton RA, Johnson C, Jacobson BS. 5-lipoxygenase and cyclooxygenase regulate wound closure in NIH/3T3 fibroblast monolayers. Am J Physiol Cell Physiol. 2004 Aug;287(2):C373-83. Epub 2004 Apr 7. PMID: 15197007
- Stockton RA, Schaefer E, Schwartz MA. p21-activated kinase regulates endothelial permeability through modulation of contractility. J Biol Chem. 2004 Nov 5;279(45):46621-30. Epub 2004 Aug 27. PMID: 15333633