Mallory D Witt, MD
Professor of Medicine, David Geffen School of Medicine at UCLA
Vice Chair for Inpatient Service, Department of Medicine, Harbor-UCLA Medical Center
Associate Chief, Division of HIV Medicine, Harbor-UCLA Medical Center
Director, HIV & Immunology Clinics, Harbor-UCLA Medical Center
HIV Medicine Research
Research DescriptionFor more than 15 years, Dr. Witt has served as site principal investigator for the Multicenter AIDS Cohort Study (MACS), the longest running natural history study of HIV disease in the United States. Alongside parallel efforts in Baltimore, Pittsburgh, and Chicago, she participates in investigations of a large cohort of HIV infected and uninfected patients who are followed for many years and assessed for rates of acquisition of HIV, as well as rates and risk factors for acquisition of hepatitis B and C. Through the MACS, she is an active participant in studies of complications of HIV infection and its therapies including metabolic, renal, cardiovascular and liver disease. She has co-authored a number of publications assessing risk factors for acquisition of hepatitis C as well as clearance of and reinfection with this virus. Dr. Witt has also served as a co-author on a large number of articles describing impact of HIV, HIV therapy, markers of immune activation, and HIV associated co-morbidities on rates of subclinical atherosclerosis.
As a co-investigator for the AIDS Clinical Trials Group (ACTG), Dr. Witt has contributed to national and international multicenter trials of antiretroviral therapies in HIV-infected patients and pregnant women; management of complications of HIV therapy; and the safety and efficacy of vaccines in HIV-infected patients.
Dr. Witt also participates in various outreach efforts in Long Beach and Los Angeles to increase awareness of HIV and the importance of HIV testing in the at-risk community.
- MD, 1985, Stanford University School of Medicine, Stanford, CA
Recent and/or Significant Publications
- Thomas GP, Li X, Post WS, Jacobson LP, Witt MD, Brown TT, Kingsley LA, Phari JP, Palella FJ Jr. Associations between antiretroviral use and subclinical coronary atherosclerosis. AIDS 2016;23:30:2477-2486.
- Seaberg EC, Witt MD, Jacobson LP, Detels R, Rinaldo CR, Margolick JB, Young S, Phair JP, Thio CL. Spontaneous clearance of the hepatitis C virus among men who have sex with men. Clin Infect Dis 2015 July 14 [Epub ahead of print]
- Post WS, Budoff M, Kingsley L, Palella RJ Jr, Witt MD, Li X, George RT, Brown TT, Jacobson LP. Associations between HIV infection and subclinical coronary atherosclerosis. Ann Intern Med 2014;160(7):458-67
- Witt MD, Seaberg EC, Darilay A, Young S, Badri S, Rinaldo CR, Jacobson LP, Detels R, Thio CL. Incident hepatitis C virus infection in men who have sex with men: a prospective cohort analysis from 1984 to 2011. Clin Infec Dis 2013;57:77-84.